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COMPOSITION BY DESIGN

Custom lipid blends & mixtures

Your components. Your ratios. Your experiment.

A research blend is a specification, not simply a collection of bottles. We discuss custom mixtures, matched comparison sets and the inclusion of hard-to-source components so that the preparation follows your study design.

Discuss this custom lipid ↗

RESEARCH-SPECIFIC, BY DESIGN

Example custom requests.

Illustrative starting briefs. Each requires confirmation of the exact structure and feasibility.

A membrane model mixture

A defined phospholipid, sphingolipid and sterol combination, including an uncommon component or a custom structural analogue.

A controlled comparison series

Several blends in which one component or ratio changes while the rest of the specification stays fixed.

An analytical research mixture

A requested set of lipid standards supplied together at individually specified concentrations for method development.

FROM IDEA TO SPECIFICATION

Make the important
details clear.

Membrane & biophysics research →

Make the ratio basis explicit.

A 70:30 molar ratio and a 70:30 mass ratio are not interchangeable when the components have different molecular weights. State the basis and whether percentages refer to all components. Include salt forms or other details that affect the mass calculation.

Separate blend preparation from formulation.

A defined lipid blend does not necessarily mean a liposome, nanoparticle or other assembled formulation. Tell us whether you need constituent lipids mixed together or an additional preparation step. Any assembly or performance work requires an agreed scope.

Plan repeated experiments from the outset.

Specify the amount per experiment and the number of replicates, then choose aliquots accordingly. Solvent compatibility, concentration, storage conditions and repeated opening should be discussed for the particular mixture. Supply is planned in screw-cap vials.

BEFORE YOU START

A few useful answers.

Can a blend contain a custom synthesized lipid?

Yes. Include that component’s full structural specification and the amount needed in the final blend so synthesis and preparation can be considered together.

Can you help clarify an incomplete blend recipe?

Yes. Send the components you know, identify the uncertain quantities and explain the study. The final recipe needs researcher approval before preparation.

How to plan a custom lipid synthesis project →

A CONVERSATION WITH CHEMISTS

Start with the question. We’ll discuss the chemistry.

Our laboratory is not yet open, but we’re ready to discuss and plan your custom lipid project.

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